Jennifer Fugo Reveals the Truth About Histamine Intolerance — And Why Your Hives Might Not Be About Food
Ever been stuck in the endless cycle of itchy rashes, mystery hives, and late-night Google rabbit holes about histamine intolerance? 😩 So many of us have been there. This week on Skin Deep MDs, we sit down with Jennifer Fugo, clinical nutritionist, licensed dietitian, and host of The Healthy Skin Show podcast (with over 1.3 million downloads!).
She’s breaking down one of the most misunderstood topics in dermatology and gut health — and why the real solution might not be another restrictive diet. 🥴
🎙️ From parasites and gut imbalances to low stomach acid and detox pathways, Jennifer explains how to look beneath the surface for what’s truly driving those stubborn, unexplained hives.
🔑 Key Takeaways
00:01:00 — What is Histamine Intolerance, Really? 🧠
Jennifer challenges the internet’s favorite buzzword, explaining why most people don’t actually have an enzyme issue — they simply have too much histamine to begin with.
00:04:00 — A Teen’s Journey: When Hives Just Won’t Quit 😳
A real-life story of a teen whose full-body hives weren’t caused by allergies or braces… but by a hidden gut infection (and yes, even baby worms 🪱).
00:10:00 — Mold, Microbes & Mystery Rashes 🧫
Not all hives are created equal. Jennifer dives into how past mold exposure, gut bacteria like H. pylori, and even travel can spark chronic urticaria (aka hives).
00:23:00 — The Liver’s Secret Role in Skin Health 🩺
From glycine to vitamin B6, discover why detox pathways (and not detox teas 😅) can influence histamine overload and skin inflammation.
00:27:00 — Why the Low-Histamine Diet Isn’t the Answer 🚫
Jennifer keeps it real: “A low-histamine diet is awful.” Think no leftovers, no citrus, no yogurt… no fun. 🥲 Instead, focus on fixing the root cause — not just what’s on your plate.
00:31:00 — Supplements That Actually Help 💊
✅ Quercetin for mast cell calm
✅ Vitamin C for antioxidant support
✅ Immunoglobulins for reducing reactivity (and yes, you can eat more foods again 👏)
00:39:00 — The One Myth She Wants Gone Forever 🔥
“Stop trying to fix hives with diet alone.” There’s always something deeper to explore — and ignoring it just keeps you stuck.
💬 Why We Love This Episode
If you’ve ever felt like your skin is “mystery itching” and no one has the answers, this conversation will make you feel seen — and give you practical steps to get your life (and skin) back. 🧘♀️💖
Jennifer’s curiosity, clinical insight, and gut-skin wisdom will make you rethink everything you thought you knew about histamine intolerance.
✨ Until next time, stay curious, keep glowing, and remember — your skin is smarter than you think. 🌸
xoxo,
The Skin Deep MDs Team 💋
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